Prof.   Farid Ataya

fataya@KSU.EDU.SA

1- Seeking novel microbial sources for cloning asparaginase gene:

    Cloning, overexpression and anticancer activity as a potential 

    therapeutic enzyme for   Acute Lymphoblastic leukemia (ALL)

2- Production, structural analysis and antimicrobial activity of 

    recombinant lipase as a potential enzybiotic 

1. Cloning, Overexpression, Bioinformatics, 

structural analyses and antimicrobial activity 

of recombinant peptidase as a potential 

enzybiotic

2. Cloning, Overexpression, Bioinformatics, 

structural analyses of recombinant Urate 

oxidase (Uricase) as a potential therapeutic 

enzyme for Tumor Lysis Syndrome (TLS)

Prof.   Salman Alrokayan

Salrokayan@KSU.EDU.SA

Mechanistic insights in the cytotoxic effects of CuO

nanoparticles on Caco-2 colon cancer cells

Development of folic acid-functionalized chitosan-PLGA

drug delivery system for the targeted delivery of eugenol 

to triple negative breast cancer cells.

Prof.   Seema Zargar

szargar@KSU.EDU.SA

Targeting the detrimental activity of immunosuppressive

cytokines by small molecules in the breast cancer cells.

Targeting the GSK3 expression and Immune checkpoint

 inhibitors by small molecules in the breast cancer cells

Dr. Mona   Shujaa

moshujaa@KSU.EDU.SA

Integrated Investigation of APOE-LXR-Associated

Immunometabolic Dysregulation in Autoimmunity.

Single-Cell Immunometabolic Atlas of Autoimmune

 Thyroid Diseases

Prof.   Abeer Alghanouchi

aalghanouchi@KSU.EDU.SA

Metabolomic Biomarkers for Breast Cancer Diagnosis

 and Disease.

Dr. Mona   Alonazi

moalonazi@KSU.EDU.SA

Dietary Fiber as a Gut-Targeted Nutritional Strategy

 ( Gut - kidney axis)

Prof.  Omar Alattas

omrattas@KSU.EDU.SA

Prof.  Mohammad Ola

mola@KSU.EDU.SA

1. Analyses of the effects of AGEs on oxidative 

    damage in cultured neuronal/glial Cells

2. Evaluation of bovine serum albumin/lysozyme

    glycation and the Inhibitory Potential of Dietary Flavonoids

3. Influence of branched-chain amino acids on the 

    oxidative damage in cultured HUVEC/neuronal/glial cells

4. Influence AGEs on the regulation of the components 

    of the renin angiotensin system in cultured retinal cells.

Analyses of AGEs signaling molecules and their 

influence on neurodegenerative damage in diabetic rat retina

Dr.  Mohamed Mahmoud

mmahmoud2@KSU.EDU.SA

Dr. Jihan   Alghamdi

jalghamdi@KSU.EDU.SA

    Against Hypervirulent Acinetobacter baumannii.

2. Molecular Characterization of Oxidative Stress-Related 

    Oncogenic Pathways in Breast Cancer

3. Biochemical and Molecular Evaluation of Oxidative Stress

    and Inflammatory Gene Signatures in Intraepithelial 

    Neoplasia Grade 3 (CIN 3) and Cervical Squamous 

    Cell Carcinoma.

4. Toll-Like and NOD-Like Receptor Signatures in the Tumor

    Microenvironment of Hepatocellular Carcinoma.

5. Innate Immune Receptor Signatures and Chemokine-Receptor

    Pathways in Cervical Squamous Cell Carcinoma.

6. Biochemical Evaluation of Oxidative Stress and Inflammatory

    Gene Expression During Respiratory Syncytial Virus Infection.

1. Universal Vaccine Targeting Hypervirulent and 

Multidrug-Resistant Klebsiella pneumoniae Through 

AI-Guided Pan-Genome Antigen Discovery

2. Transcriptomic Profiling of Oncogenes, Tumor 

Suppressor Genes, and Oxidative Stress Biomarkers 

in Peripheral Blood Mononuclear Cells of Diabetic Patients

3. Chemokine-Receptor Network Dysregulation and 

Tumor Immune Microenvironment Remodeling in 

Breast Cancer and Cervical Squamous Cell Carcinoma

4. Integrated Molecular Crosstalk Between Inflammation, 

Oxidative Stress, and Oncogenic Signaling in Cervical 

Squamous Cell Carcinoma

5. Chemokine (CXCL/CXCR) Expression Profiles in 

Respiratory Syncytial Virus-Induced Inflammatory 

Responses

Dr.  Foza Alenizy

falenizy@KSU.EDU.SA

 Protein Phosphatase 2A Dysfunction in Astrocyte Activation and

 Neuroinflammation in Alzheimer's Disease.

Dr.  Amal Alenad

aalenad@KSU.EDU.SA

Optimizing Microbial DNA Extraction and Host DNA Depletion Strategies for Food Shotgun Metagenomics

Metagenomic Characterization of Bacterial Communities in Compressed Sukari and Khalas Dates and the Influence of Processing Practices

Prof.  Ajamaluddin Malik

amalik@KSU.EDU.SA

A concentration-dependent study will explore how CTAB 

induces concentration-dependent unfolding and amyloid 

fibrillation of protein under physiological conditions, and its 

effect modulated by folding additives. The work provides insights 

into protein misfolding relevant to biopharmaceutical stability.

1. Deciphering the mechanisms and modulation of 

α-synuclein amyloidogenesis. This project addresses 

alpha-synuclein aggregation involved in 

Parkinson’s disease.

2. A molecular approach to understanding and 

inhibiting lysozyme amyloidogenesis

This project investigates how lysozyme proteins misfold

 and form harmful amyloid fibrils, providing insights 

into hereditary amyloidosis and other 

protein-misfolding diseases.

Dr.  Nouf Alafaleg

nalafaleg@KSU.EDU.SA

1. Functional Validation of Rare IBD-Associated Variants

    through Integrative Transcriptomic and Proteomic 

    Profiling in a Saudi Cohort.

2. Investigating the Potential of Biogenic Nanoparticles to 

    Modulate the Glycation-Proteostasis Axis

In Silico-Guided Design and Biogenic Synthesis of 

Multifunctional Nanoparticles for Targeted Modulation

 of Pathological Protein Aggregation

Dr.  Amal Albati

aalbity@KSU.EDU.SA

Targeting Chemotherapy induced Senescence Using Natural

Compounds in Cancer Cells

Evaluating the Effects of Thymoquinone on 

Functional, Molecular and genetic Markers of 

Aging in Wild Type Mice

Dr.  Salman Alamery

salamery@KSU.EDU.SA

Gene expression and functional analysis of DNA repair pathway

 genes in colon cancer cell lines in response to fisetin

Exploring the molecular targets and mechanisms 

of fiestin on induced colorectal cancer in mice or rats

Prof.  Sooad Al-Daihan

sdaihan@KSU.EDU.SA

1. Enhancing the Effect of Anticancer Drugs Using Nanoparticles:

    A Synergistic Approach to Sensitize Cancer Cells

2. Green-Synthesized Nanoparticles as Potential Anticancer 

    Nano-Therapeutics: Biological Activity and Mechanistic 

    Evaluation in Cancer Cell Lines

Development of Multifunctional Anticancer 

Nanoparticles for Precision Cancer Therapy: 

From Synthesis to Mechanistic Validation

Healing Through the Gut: A Novel Approach 

to Controlling Inflammation and Restoring Immune Balance